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Cholestatic jaundice


Pathology:

This may be divided into extra-hepatic and intra-hepatic cholestasis.

Extra-hepatic cholestasis:

Is due to large duct obstruction of bile flow at any point in the biliary tree distal to the bile canaliculi

Intra-hepatic cholestasis:

Due to failure of bile secretion


Clinical features:

Jaundice

Pale stools

Dark urine

Raised serum conjugated bilirubin

 

 


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