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Cholestatic jaundice Pathology: This may be divided into extra-hepatic and intra-hepatic cholestasis. Extra-hepatic cholestasis: Is due to large duct obstruction of bile flow at any point in the biliary tree distal to the bile canaliculi Intra-hepatic cholestasis: Due to failure of bile secretion Clinical features: Jaundice Pale stools Dark urine Raised serum conjugated bilirubin |
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