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Anaemia of chronic disease


Occurs in patients with:

Chronic infections (e.g. TB, infective endocarditis, osteomyelitis)

Chronic inflammatory diseases (e.g. RA, SLE, polymyalgia rheumatica)

Malignancies


Pathology:

  • Unclear
  • There is decreased release of Fe from the bone marrow to developing erythroblasts
  • Inadequate EPO response to the anaemia
  • Decreased RBC survival

Treatment:

  • Involves treating the underlying disease

 


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