medicnotes.org.uk :: Blood components

Blood, blood components and blood products

What is available to be transfused?

Whole blood
Packed red cells
Red cell concentrates
Buffy-coat depleted red cell concentrates - most WBCs and platelets removed
Leucocyte-depleted red cell concentrates – used to prevent alloimmunisation to leucocyte antigens (e.g. in aplastic anaemia patients who are potential recipients of allogeneic BM transplants)
Washed red cell concentrates – used in patients who have had anaphylactic reactions
Platelet concentrates
Granulocyte concentrates
Fresh frozen plasma (FFP) – contains all the coagulation factors present in fresh plasma
Cryoprecipitate – contains factor VIII, vWF and fibrinogen
Factor VIII and IX concentrates
Albumin
Normal immunoglobulin – used in patients with hypogammaglobulinaemia
Specific immunoglobulins – e.g. anti-hepatitis B


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	Blood, blood components and blood products What is available to be transfused? Whole blood Packed red cells Red cell concentrates Buffy-coat depleted red cell concentrates - most WBCs and platelets removed Leucocyte-depleted red cell concentrates – used to prevent alloimmunisation to leucocyte antigens (e.g. in aplastic anaemia patients who are potential recipients of allogeneic BM transplants) Washed red cell concentrates – used in patients who have had anaphylactic reactions Platelet concentrates Granulocyte concentrates Fresh frozen plasma (FFP) – contains all the coagulation factors present in fresh plasma Cryoprecipitate – contains factor VIII, vWF and fibrinogen Factor VIII and IX concentrates Albumin Normal immunoglobulin – used in patients with hypogammaglobulinaemia Specific immunoglobulins – e.g. anti-hepatitis B
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